Multidrug efflux protein that confers resistance to a wide range of toxic compounds, including ethidium, methyl viologen, acriflavine, ...
People also ask
What is the function of the EmrE gene?
In bacterial cells, EmrE removes toxic compounds by active transport through the plasma membrane, lowering their cytosolic concentration. However, yeast cells expressing HA-EmrE take up 14C-methyl viologen as well as control cells do.
What is the opposite of a Homodimer?
A protein homodimer is formed by two identical proteins while a protein heterodimer is formed by two different proteins.
Dec 13, 2013 · EMRE is a 10-kilodalton, metazoan-specific protein with a single transmembrane domain. In its absence, uniporter channel activity was lost ...
EmrE is a highly hydrophobic 12-kDa protein that has been purified by taking advantage of its unique solubility in organic solvents. After solubilization and ...
Jan 8, 2021 · The dimeric transporter, EmrE, effluxes polyaromatic cationic drugs in a proton-coupled manner to confer multidrug resistance in bacteria.
EmrE is a bacterial transporter protein that forms an anti-parallel homodimer with four transmembrane helices in each monomer. EmrE transports positively ...
Aug 6, 2018 · We use computer simulations to design inhibitors of the Escherichia coli multidrug resistance protein EmrE (efflux-multidrug resistance E) from ...
This gene encodes a core regulatory component of a calcium channel in the mitochondrial inner membrane. [provided by RefSeq, Apr 2017] See more...
EMRE is a single-pass membrane protein that in cultured cells is essential for calcium uptake (22). Studies suggest that EMRE acts as a molecular scaffold, ...
Oct 22, 2019 · EmrE is a native E. coli transporter that couples drug efflux of cationic/aromatic compounds with the proton gradient (Schuldiner, 2009). It has ...
EmrE is a small multidrug transporter (110 amino acids long) from Escherichia coli that extrudes various drugs in exchange with protons, thereby rendering ...